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BACKGROUND: Neglected tropical diseases (NTDs) disproportionately affect populations living in resource-limited settings. In the Amazon basin, substantial numbers of NTDs are zoonotic, transmitted by vertebrate (dogs, bats, snakes) and invertebrate species (sand flies and triatomine insects). However, no dedicated consortia exist to find commonalities in the risk factors for or mitigations against bite-associated NTDs such as rabies, snake envenoming, Chagas disease and leishmaniasis in the region. The rapid expansion of COVID-19 has further reduced resources for NTDs, exacerbated health inequality and reiterated the need to raise awareness of NTDs related to bites. METHODS: The nine countries that make up the Amazon basin have been considered (Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Peru, Surinam and Venezuela) in the formation of a new network. RESULTS: The Amazonian Tropical Bites Research Initiative (ATBRI) has been created, with the aim of creating transdisciplinary solutions to the problem of animal bites leading to disease in Amazonian communities. The ATBRI seeks to unify the currently disjointed approach to the control of bite-related neglected zoonoses across Latin America. CONCLUSIONS: The coordination of different sectors and inclusion of all stakeholders will advance this field and generate evidence for policy-making, promoting governance and linkage across a One Health arena.
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COVID-19 , Saúde Única , Mordeduras de Serpentes , Medicina Tropical , Humanos , Animais , Cães , Antivenenos , Disparidades nos Níveis de Saúde , Venenos de Serpentes , Doenças NegligenciadasRESUMO
Hepatic Fasciola is a frequent disease in the Peruvian highlands. We present a case of hepatic Fasciola from the Andean zone of La Libertad, with symptoms of several months of evolution with pain in the right hypochondrium, jaundice and coluria. An abdominal CT scan was performed, demonstrating a liver mass probable neoplasm, and was referred to the Institute of Neoplastic Diseases. Laboratory tests were completed finding eosinophilia and variable increases in liver function tests. Fascioliasis was presented as a differential diagnosis and a Western Bloot examination was performed confirming its diagnosis. Treatment with 2 cycles of Triclabendazole was started, with a favorable clinical evolution.
Assuntos
Fasciola hepatica , Fasciolíase , Neoplasias Hepáticas , Animais , Humanos , Neoplasias Hepáticas/diagnóstico por imagem , Tomografia Computadorizada por Raios X , TriclabendazolRESUMO
La Fasciola hepática es una enfermedad frecuente en sierra del Perú. Presentamos un caso de Fasciola hepática procedente de la zona andina de La Libertad, con sintomatología de varios meses de evolución con dolor en hipocondrio derecho, ictericia y coluria. Se realizó TAC abdominal demostrándose una masa hepática probable neoplasia, derivándose a Instituto de Enfermedades Neoplásicas. Se completó los exámenes de laboratorio encontrando eosinofilia y aumentos variables de las pruebas de función hepática. Se planteó como diagnóstico diferencial Fascioliasis y se realizó examen de Western Bloot confirmándose su diagnóstico. Se inició tratamiento con 2 ciclos de Triclabendazol, con evolución clínica favorable.
Hepatic Fasciola is a frequent disease in the Peruvian highlands. We present a case of hepatic Fasciola from the Andean zone of La Libertad, with symptoms of several months of evolution with pain in the right hypochondrium, jaundice and coluria. An abdominal CT scan was performed, demonstrating a liver mass probable neoplasm, and was referred to the Institute of Neoplastic Diseases. Laboratory tests were completed finding eosinophilia and variable increases in liver function tests. Fascioliasis was presented as a differential diagnosis and a Western Bloot examination was performed confirming its diagnosis. Treatment with 2 cycles of Triclabendazole was started, with a favorable clinical evolution.
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Los coronavirus han estado presentes entre los humanos hace décadas, causando entre el 10 - 30% de los resfríos comunes en los humanos. Dos coronavirus han causado pandemias y alertas globales en las últimas décadas: SARS-CoV Y MERS-CoV. SARS-CoV-2 es el séptimo coronavirus en generar una infección en humanos, y el tercero en generar una pandemia. En este artículo, presentamos y comparamos la cronología, epidemiología y las medidas de control de cada una de las pandemias: SARS, MERS y COVID-19. (AU)
Coronaviruses have been present in humans for decades, causing 10-30% of common colds in humans. Two coronaviruses have caused global pandemics and alerts in recent decades: SARS-CoV and MERS-CoV. SARS-CoV-2 is the seventh coronavirus to generate an infection in humans, and the third to generate a pandemic. In this article, we present and compare the chronology, epidemiology, and control measures of each of the pandemics: SARS, MERS and COVID-19. (AU)
Assuntos
Humanos , Infecções por Coronavirus/epidemiologia , Coronavirus , Coronavírus Relacionado à Síndrome Respiratória Aguda Grave , Coronavírus da Síndrome Respiratória do Oriente MédioRESUMO
Resumen Esta revisión sobre mordedura de serpiente (ofidismo), buscar actualizar la epidemiologia clínica y terapia de la patología frecuente en la selva y costa peruana. Entre las serpientes venenosas destaca el accidente producido por el género Bothrops, en el Perú la especie B. atrox (Jergón de la selva) es el causante en más del 90% de los casos.
Summary This review on snake bites, seek to update the clinical epidemiology and therapy of frequent pathology in the Peruvian jungle and coast. Among the venomous snakes, the accident caused by the genus Bothrops stands out, in Peru the species B. atrox (jungle jar) is the cause in more than 90% of cases.
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OBJECTIVE: To establish the relationship among age, sex, body mass index, consumption of alcoholic beverages and cigarettes with the inadequate response to the vaccine against Hepatitis B in patients with HIV infection who were treated in the Clinical Unit of Infectious and Tropical Diseases of the Regional Hospital of Trujillo - Peru, from 2014 to 2015. MATERIALS AND METHODS: The study was observational, retrospective, cross-sectional, type cases and controls. RESULTS: In the vaccinated patients, it was found that the age ≥ 50 years old; with OR = 3.4 and CD4 < 200, with OR = 35.0, are the risk factors to get the inadequate response to the vaccine against Hepatitis B. CONCLUSIONS: There is a relationship between the re-count of cells CD4 < 00 and the age over 50 years old with an Inadequate response to the vaccination against hepatitis B in HIV-infected patients in the Regional Hospital of Trujillo.
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Infecções por HIV/imunologia , Vacinas contra Hepatite B/imunologia , Imunogenicidade da Vacina , Fatores Etários , Consumo de Bebidas Alcoólicas/efeitos adversos , Índice de Massa Corporal , Fumar Cigarros/efeitos adversos , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores SexuaisRESUMO
La Enfermedad de Carrión es una enfermedad endémica en el Perú, causada por la Bartonella bacilliformis, cursa con un estadio agudo o anemizante, una forma verrucosa y bacteriemia asintomática. La forma aguda es grave y tiene alta morbilidad y mortalidad. Se reporta el caso de una mujer joven, gestante, procedente de Yungay, Ancash, quien cursó la fase aguda complicada con disfunción multiorgánica, síndrome de dificultad respiratoria aguda que requirió ventilación mecánica en posición prona, cuya evolución fue desfavorable y falleció.
Carrion´s disease is an endemic disease in Peru caused by Bartonella bacilliformis presenting with an acute or hemolytic form and a chronic verrucous form with asymptomatic bacteremia. The acute form is usually serious and is associated with high morbidity and mortality. We report the case of a case of a young pregnant woman from Yungay, Ancash who presented with the acute form complicated with multi organ failure and acute respiratory distress syndrome needing mechanical ventilation and dying.
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El uso de los antibióticos desde los años 40 del siglo pasado permitió disminuir en forma importante y notable la morbilidad y mortalidad a nivel mundial. Sin embargo, la aparición de la resistencia antimicrobiana ha hecho que el tratamiento de las enfermedades infecciosas, se vuelva una tarea desafiante para el médico que debe brindar opciones terapéuticas, racionales y basadas en evidencias para mejorar la salud de los pacientes. Esta revisión brinda una visión panorámica sobre la gravedad de este problema y el papel preponderante que deben asumir los sistemas de salud en el apoyo a los profesionales de la salud y en la educación de los pacientes para llegar al ansiado uso racional de estos medicamentos.
The use of antibiotics since mid-twentieth century significantly reduced morbidity and mortality worldwide. However, the emergence of antimicrobial resistance has made therapy of infectious diseases a challenging task for physicians, who must provide therapeutic, rational and evidence-based options aiming to improve their patients health. This review provides an overview on how serious the current situation and the paramount role is that health systems must play in supporting healthcare professionals and educating patients in order to achieve rational use of these medications.
